Innovating for the Global South: New book offers practical insights


Press Release: “Despite the vast wealth generated in the last half century, in today’s world inequality is worsening and poverty is becoming increasingly chronic. Hundreds of millions of people continue to live on less than $2 per day and lack basic human necessities such as nutritious food, shelter, clean water, primary health care, and education.
Innovating for the Global South: Towards an Inclusive Innovation Agenda, the latest book from Rotman-UTP Publishing and the first volume in the Munk Series on Global Affairs, offers fresh solutions for reducing poverty in the developing world. Highlighting the multidisciplinary expertise of the University of Toronto’s Global Innovation Group, leading experts from the fields of engineering, public health, medicine, management, and public policy examine the causes and consequences of endemic poverty and the challenges of mitigating its effects from the perspective of the world’s poorest of the poor.
Can we imagine ways to generate solar energy to run essential medical equipment in the countryside? Can we adapt information and communication technologies to provide up-to-the-minute agricultural market prices for remote farming villages? How do we create more inclusive innovation processes to hear the voices of those living in urban slums? Is it possible to reinvent a low-cost toilet that operates beyond the water and electricity grids?
Motivated by the imperatives of developing, delivering, and harnessing innovation in the developing world, Innovating for the Global South is essential reading for managers, practitioners, and scholars of development, business, and policy.
“As we see it, Innovating for the Global South is fundamentally about innovating scalable solutions that mitigate the effects of poverty and underdevelopment in the Global South. It is not about inventing some new gizmo for some untapped market in the developing world,” say Profs. Dilip Soman and Joseph Wong of the UofT, who are two of the editors of the volume.
The book is edited and also features contributions by three leading UofT thinkers who are tackling innovation in the global south from three different academic perspectives.

  • Dilip Soman is Corus Chair in Communication Strategy and a professor of Marketing at the Rotman School of Management.
  • Janice Gross Stein is the Belzberg Professor of Conflict Management in the Department of Political Science and Director of the Munk School of Global Affairs.
  • Joseph Wong is Ralph and Roz Halbert Professor of Innovation at the Munk School of Global Affairs and Canada Research Chair in Democratization, Health, and Development in the Department of Political Science.

The chapters in the book address the process of innovation from a number of vantage points.
Introduction: Rethinking Innovation – Joseph Wong and Dilip Soman
Chapter 1: Poverty, Invisibility, and Innovation – Joseph Wong
Chapter 2: Behaviourally Informed Innovation – Dilip Soman
Chapter 3: Appropriate Technologies for the Global South – Yu-Ling Cheng (University of Toronto, Chemical Engineering and Applied Chemistry) and Beverly Bradley (University of Toronto, Centre for Global Engineering)
Chapter 4: Globalization of Biopharmaceutical Innovation: Implications for Poor-Market Diseases – Rahim Rezaie (University of Toronto, Munk School of Global Affairs, Research Fellow)
Chapter 5: Embedded Innovation in Health – Anita M. McGahan (University of Toronto, Rotman School of Management, Associate Dean of Research), Rahim Rezaie and Donald C. Cole (University of Toronto, Dalla Lana School of Public Health)
Chapter 6: Scaling Up: The Case of Nutritional Interventions in the Global South – Ashley Aimone Phillips (Registered Dietitian), Nandita Perumal (University of Toronto, Doctoral Fellow, Epidemiology), Carmen Ho (University of Toronto, Doctoral Fellow, Political Science), and Stanley Zlotkin (University of Toronto and the Hospital for Sick Children,Paediatrics, Public Health Sciences and Nutritional Sciences)
Chapter 7: New Models for Financing Innovative Technologies and Entrepreneurial Organizations in the Global South – Murray R. Metcalfe (University of Toronto, Centre for Global Engineering, Globalization)
Chapter 8: Innovation and Foreign Policy – Janice Gross Stein
Conclusion: Inclusive Innovation – Will Mitchell (University of Toronto, Rotman School of Management, Strategic Management), Anita M. McGahan”

Selected Readings on Behavioral Economics: Nudges


The Living Library’s Selected Readings series seeks to build a knowledge base on innovative approaches for improving the effectiveness and legitimacy of governance. This curated and annotated collection of recommended works on the topic of behavioral economics was originally published in 2014.

The 2008 publication of Richard Thaler and Cass Sunstein’s Nudge ushered in a new era of behavioral economics, and since then, policy makers in the United States and elsewhere have been applying behavioral economics to the field of public policy. Like Smart Disclosure, behavioral economics can be used in the public sector to improve the decisionmaking ability of citizens without relying on regulatory interventions. In the six years since Nudge was published, the United Kingdom has created the Behavioural Insights Team (also known as the Nudge Unit), a cross-ministerial organization that uses behavioral economics to inform public policy, and the White House has recently followed suit by convening a team of behavioral economists to create a behavioral insights-driven team in the United States. Policymakers have been using behavioral insights to design more effective interventions in the fields of long term unemployment; roadway safety; enrollment in retirement plans; and increasing enrollment in organ donation registries, to name some noteworthy examples. The literature of this nascent field provides a look at the growing optimism in the potential of applying behavioral insights in the public sector to improve people’s lives.

Selected Reading List (in alphabetical order)

  • John Beshears, James Choi, David Laibson and Brigitte C. Madrian – The Importance of Default Options for Retirement Savings Outcomes: Evidence from the United States – a paper examining the role default options play in encouraging intelligent retirement savings decisionmaking.
  • Cabinet Office and Behavioural Insights Team, United Kingdom – Applying Behavioural Insights to Healtha paper outlining some examples of behavioral economics being applied to the healthcare landscape using cost-efficient interventions.
  • Matthew Darling, Saugato Datta and Sendhil Mullainathan – The Nature of the BEast: What Behavioral Economics Is Not – a paper discussing why control and behavioral economics are not as closely aligned as some think, reiterating the fact that the field is politically agnostic.
  • Antoinette Schoar and Saugato Datta – The Power of Heuristics – a paper exploring the concept of “heuristics,” or rules of thumb, which can provide helpful guidelines for pushing people toward making “reasonably good” decisions without a full understanding of the complexity of a situation.
  • Richard H. Thaler and Cass R. Sunstein – Nudge: Improving Decisions About Health, Wealth, and Happiness – an influential book describing the many ways in which the principles of behavioral economics can be and have been used to influence choices and behavior through the development of new “choice architectures.” 
  • U.K. Parliament Science and Technology Committee – Behaviour Changean exploration of the government’s attempts to influence the behaviour of its citizens through nudges, with a focus on comparing the effectiveness of nudges to that of regulatory interventions.

Annotated Selected Reading List (in alphabetical order)

Beshears, John, James Choi, David Laibson and Brigitte C. Madrian. “The Importance of Default Options for Retirement Savings Outcomes: Evidence from the United States.” In Jeffrey R. Brown, Jeffrey B. Liebman and David A. Wise, editors, Social Security Policy in a Changing Environment, Cambridge: National Bureau of Economic Research, 2009. http://bit.ly/LFmC5s.

  • This paper examines the role default options play in pushing people toward making intelligent decisions regarding long-term savings and retirement planning.
  • Importantly, the authors provide evidence that a strategically oriented default setting from the outset is likely not enough to fully nudge people toward the best possible decisions in retirement savings. They find that the default settings in every major dimension of the savings process (from deciding whether to participate in a 401(k) to how to withdraw money at retirement) have real and distinct effects on behavior.

Cabinet Office and Behavioural Insights Team, United Kingdom. “Applying Behavioural Insights to Health.” December 2010. http://bit.ly/1eFP16J.

  • In this report, the United Kingdom’s Behavioural Insights Team does not attempt to “suggest that behaviour change techniques are the silver bullet that can solve every problem.” Rather, they explore a variety of examples where local authorities, charities, government and the private-sector are using behavioural interventions to encourage healthier behaviors.  
  • The report features case studies regarding behavioral insights ability to affect the following public health issues:
    • Smoking
    • Organ donation
    • Teenage pregnancy
    • Alcohol
    • Diet and weight
    • Diabetes
    • Food hygiene
    • Physical activity
    • Social care
  • The report concludes with a call for more experimentation and knowledge gathering to determine when, where and how behavioural interventions can be most effective in helping the public become healthier.

Darling, Matthew, Saugato Datta and Sendhil Mullainathan. “The Nature of the BEast: What Behavioral Economics Is Not.” The Center for Global Development. October 2013. https://bit.ly/2QytRmf.

  • In this paper, Darling, Datta and Mullainathan outline the three most pervasive myths that abound within the literature about behavioral economics:
    • First, they dispel the relationship between control and behavioral economics.  Although tools used within behavioral economics can convince people to make certain choices, the goal is to nudge people to make the choices they want to make. For example, studies find that when retirement savings plans change the default to opt-in rather than opt-out, more workers set up 401K plans. This is an example of a nudge that guides people to make a choice that they already intend to make.
    • Second, they reiterate that the field is politically agnostic. Both liberals and conservatives have adopted behavioral economics and its approach is neither liberal nor conservative. President Obama embraces behavioral economics but the United Kingdom’s conservative party does, too.
    • And thirdly, the article highlights that irrationality actually has little to do with behavioral economics. Context is an important consideration when one considers what behavior is rational and what behavior is not. Rather than use the term “irrational” to describe human beings, the authors assert that humans are “infinitely complex” and behavior that is often considered irrational is entirely situational.

Schoar, Antoinette and Saugato Datta. “The Power of Heuristics.” Ideas42. January 2014. https://bit.ly/2UDC5YK.

  • This paper explores the notion that being presented with a bevy of options can be desirable in many situations, but when making an intelligent decision requires a high-level understanding of the nuances of vastly different financial aid packages, for example, options can overwhelm. Heuristics (rules of thumb) provide helpful guidelines that “enable people to make ‘reasonably good’ decisions without needing to understand all the complex nuances of the situation.”
  • The underlying goal heuristics in the policy space involves giving people the type of “rules of thumb” that enable make good decisionmaking regarding complex topics such as finance, healthcare and education. The authors point to the benefit of asking individuals to remember smaller pieces of knowledge by referencing a series of studies conducted by psychologists Beatty and Kahneman that showed people were better able to remember long strings of numbers when they were broken into smaller segments.
  • Schoar and Datta recommend these four rules when implementing heuristics:
    • Use heuristics where possible, particularly in complex situation;
    • Leverage new technology (such as text messages and Internet-based tools) to implement heuristics.
    • Determine where heuristics can be used in adult training programs and replace in-depth training programs with heuristics where possible; and
    • Consider how to apply heuristics in situations where the exception is the rule. The authors point to the example of savings and credit card debt. In most instances, saving a portion of one’s income is a good rule of thumb. However, when one has high credit card debt, paying off debt could be preferable to building one’s savings.

Thaler, Richard H. and Cass R. Sunstein. Nudge: Improving Decisions About Health, Wealth, and Happiness. Yale University Press, 2008. https://bit.ly/2kNXroe.

  • This book, likely the single piece of scholarship most responsible for bringing the concept of nudges into the public consciousness, explores how a strategic “choice architecture” can help people make the best decisions.
  • Thaler and Sunstein, while advocating for the wider and more targeted use of nudges to help improve people’s lives without resorting to overly paternal regulation, look to five common nudges for lessons and inspiration:
    • The design of menus gets you to eat (and spend) more;
    • “Flies” in urinals improve, well, aim;
    • Credit card minimum payments affect repayment schedules;
    • Automatic savings programs increase savings rate; and
    • “Defaults” can improve rates of organ donation.
  • In the simplest terms, the authors propose the wider deployment of choice architectures that follow “the golden rule of libertarian paternalism: offer nudges that are most likely to help and least likely to inflict harm.”

U.K. Parliament Science and Technology Committee. “Behaviour Change.” July 2011. http://bit.ly/1cbYv5j.

  • This report from the U.K.’s Science and Technology Committee explores the government’s attempts to influence the behavior of its citizens through nudges, with a focus on comparing the effectiveness of nudges to that of regulatory interventions.
  • The author’s central conclusion is that, “non-regulatory measures used in isolation, including ‘nudges,’ are less likely to be effective. Effective policies often use a range of interventions.”
  • The report’s other major findings and recommendations are:
    • Government must invest in gathering more evidence about what measures work to influence population behaviour change;
    • They should appoint an independent Chief Social Scientist to provide them with robust and independent scientific advice;
    • The Government should take steps to implement a traffic light system of nutritional labelling on all food packaging; and
    • Current voluntary agreements with businesses in relation to public health have major failings. They are not a proportionate response to the scale of the problem of obesity and do not reflect the evidence about what will work to reduce obesity. If effective agreements cannot be reached, or if they show minimal benefit, the Government should pursue regulation.”

DARPA Open Catalog Makes Agency-Sponsored Software and Publications Available to All


Press Release: “Public website aims to encourage communities interested in DARPA research to build off the agency’s work, starting with big data…
DARPA has invested in many programs that sponsor fundamental and applied research in areas of computer science, which have led to new advances in theory as well as practical software. The R&D community has asked about the availability of results, and now DARPA has responded by creating the DARPA Open Catalog, a place for organizing and sharing those results in the form of software, publications, data and experimental details. The Catalog can be found at http://go.usa.gov/BDhY.
Many DoD and government research efforts and software procurements contain publicly releasable elements, including open source software. The nature of open source software lends itself to collaboration where communities of developers augment initial products, build on each other’s expertise, enable transparency for performance evaluation, and identify software vulnerabilities. DARPA has an open source strategy for areas of work including big data to help increase the impact of government investments in building a flexible technology base.
“Making our open source catalog available increases the number of experts who can help quickly develop relevant software for the government,” said Chris White, DARPA program manager. “Our hope is that the computer science community will test and evaluate elements of our software and afterward adopt them as either standalone offerings or as components of their products.”

"Natural Cities" Emerge from Social Media Location Data


Emerging Technology From the arXiv: “Nobody agrees on how to define a city. But the emergence of “natural cities” from social media data sets may change that, say computational geographers…
A city is a large, permanent human settlement. But try and define it more carefully and you’ll soon run into trouble. A settlement that qualifies as a city in Sweden may not qualify in China, for example. And the reasons why one settlement is classified as a town while another as a city can sometimes seem almost arbitrary.
City planners know this problem well.  They tend to define cities by administrative, legal or even historical boundaries that have little logic to them. Indeed, the same city can sometimes be defined in various different ways.
That causes all kinds of problems from counting the total population to working out who pays for the upkeep of the place.  Which definition do you use?
Now help may be at hand thanks to the work of Bin Jiang and Yufan Miao at the University of Gävle in Sweden. These guys have found a way to use people’s location recorded by social media to define the boundaries of so-called natural cities which have a close resemblance to real cities in the US.
Jiang and Miao began with a dataset from the Brightkite social network, which was active between 2008 and 2010. The site encouraged users to log in with their location details so that they could see other users nearby. So the dataset consists of almost 3 million locations in the US and the dates on which they were logged.
To start off, Jiang and Miao simply placed a dot on a map at the location of each login. They then connected these dots to their neighbours to form triangles that end up covering the entire mainland US.
Next, they calculated the size of each triangle on the map and plotted this size distribution, which turns out to follow a power law. So there are lots of tiny triangles but only a few  large ones.
Finally, the calculated the average size of the triangles and then coloured in all those that were smaller than average. The coloured areas are “natural cities”, say Jiang and Miao.
It’s easy to imagine that resulting map of triangles is of little value.  But to the evident surprise of ther esearchers, it produces a pretty good approximation of the cities in the US. “We know little about why the procedure works so well but the resulting patterns suggest that the natural cities effectively capture the evolution of real cities,” they say.
That’s handy because it suddenly gives city planners a way to study and compare cities on a level playing field. It allows them to see how cities evolve and change over time too. And it gives them a way to analyse how cities in different parts of the world differ.
Of course, Jiang and Miao will want to find out why this approach reveals city structures in this way. That’s still something of a puzzle but the answer itself may provide an important insight into the nature of cities (or at least into the nature of this dataset).
A few days ago, this blog wrote about how a new science of cities is emerging from the analysis of big data.  This is another example and expect to see more.
Ref:  http://arxiv.org/abs/1401.6756 : The Evolution of Natural Cities from the Perspective of Location-Based Social Media”

Where next for citizen science? Innovative uses for crowd sourcing


VIDEO: “Thanks to new technologies , citizen science has seen huge growth over the past decade, opening up important scientific research to the masses and harnessing the power of the crowd. Ranging from classifying new galaxies to monitoring wildlife in the Serengeti, the Zooniverse stable of citizen science projects led by Dr Chris Lintott has seen incredible success. But what does the future hold for citizen science — does it have the power to help in real life situations such as disaster zones? And what are the implications when dealing with huge amounts of potentially sensitive data in real time?
This seminar is part of the Oxford Martin School Hilary Term seminar series: Blurring the lines: the changing dynamics between man and machine…www.oxfordmartin.ox.ac.uk”

The Impact of the Social Sciences


New book:  The Impact of the Social Sciences: How Academics and Their Research Make a Difference by Simon Bastow, Jane Tinkler and Patrick Dunleavy. 
The three-year Impact of Social Sciences Project has culminated in a monograph published by SAGE. The book presents thorough analysis of how academic research in the social sciences achieves public policy impacts, contributes to economic prosperity, and informs public understanding of policy issues as well as economic and social changes. This book is essential reading for academics, researchers, university administrators, government and private funders, and anyone interested in the global conversation about joining up and increasing the societal value and impact of social science knowledge and research.
figure214Resources:

  • View the data visualisations that appear in the book here.
  • Browse our Living Bibliography with links to further resources.
  • Research Design and Methods Appendix [PDF]
  • “Assessing the Impacts of Academic Social Science Research: Modelling the economic impact on the UK economy of UK-based academic social science research” [PDF] A report prepared for the LSE Public Policy Group by Cambridge Econometrics.

Research Blogs:

It’s the Neoliberalism, Stupid: Why instrumentalist arguments for Open Access, Open Data, and Open Science are not enough.


Eric Kansa at LSE Blog: “…However, I’m increasingly convinced that advocating for openness in research (or government) isn’t nearly enough. There’s been too much of an instrumentalist justification for open data an open access. Many advocates talk about how it will cut costs and speed up research and innovation. They also argue that it will make research more “reproducible” and transparent so interpretations can be better vetted by the wider community. Advocates for openness, particularly in open government, also talk about the wonderful commercial opportunities that will come from freeing research…
These are all very big policy issues, but they need to be asked if the Open Movement really stands for reform and not just a further expansion and entrenchment of Neoliberalism. I’m using the term “Neoliberalism” because it resonates as a convenient label for describing how and why so many things seem to suck in Academia. Exploding student debt, vanishing job security, increasing compensation for top administrators, expanding bureaucracy and committee work, corporate management methodologies (Taylorism), and intensified competition for ever-shrinking public funding all fall under the general rubric of Neoliberalism. Neoliberal universities primarily serve the needs of commerce. They need to churn out technically skilled human resources (made desperate for any work by high loads of debt) and easily monetized technical advancements….
“Big Data,” “Data Science,” and “Open Data” are now hot topics at universities. Investments are flowing into dedicated centers and programs to establish institutional leadership in all things related to data. I welcome the new Data Science effort at UC Berkeley to explore how to make research data professionalism fit into the academic reward systems. That sounds great! But will these new data professionals have any real autonomy in shaping how they conduct their research and build their careers? Or will they simply be part of an expanding class of harried and contingent employees- hired and fired through the whims of creative destruction fueled by the latest corporate-academic hype-cycle?
Researchers, including #AltAcs and “data professionals”, need  a large measure of freedom. Miriam Posner’s discussion about the career and autonomy limits of Alt-academic-hood help highlight these issues. Unfortunately, there’s only one area where innovation and failure seem survivable, and that’s the world of the start-up. I’ve noticed how the “Entrepreneurial Spirit” gets celebrated lots in this space. I’m guilty of basking in it myself (10 years as a quasi-independent #altAc in a nonprofit I co-founded!).
But in the current Neoliberal setting, being an entrepreneur requires a singular focus on monetizing innovation. PeerJ and Figshare are nice, since they have business models that less “evil” than Elsevier’s. But we need to stop fooling ourselves that the only institutions and programs that we can and should sustain are the ones that can turn a profit. For every PeerJ or Figshare (and these are ultimately just as dependent on continued public financing of research as any grant-driven project), we also need more innovative organizations like the Internet Archive, wholly dedicated to the public good and not the relentless pressure to commoditize everything (especially their patrons’ privacy). We need to be much more critical about the kinds of programs, organizations, and financing strategies we (as a society) can support. I raised the political economy of sustainability issue at a recent ThatCamp and hope to see more discussion.
In reality so much of the Academy’s dysfunctions are driven by our new Gilded Age’s artificial scarcity of money. With wealth concentrated in so few hands, it is very hard to finance risk taking and entreprenurialism in the scholarly community, especially to finance any form of entrepreneurialism that does not turn a profit in a year or two.
Open Access and Open Data will make so much more of a difference if we had the same kind of dynamism in the academic and nonprofit sector as we have in the for-profit start-up sector. After all, Open Access and Open Data can be key enablers to allow much broader participation in research and education. However, broader participation still needs to be financed: you cannot eat an open access publication. We cannot gloss over this key issue.
We need more diverse institutional forms so that researchers can find (or found) the kinds of organizations that best channel their passions into contributions that enrich us all. We need more diverse sources of financing (new foundations, better financed Kickstarters) to connect innovative ideas with the capital needed to see them implemented. Such institutional reforms will make life in the research community much more livable, creative, and dynamic. It would give researchers more options for diverse and varied career trajectories (for-profit or not-for-profit) suited to their interests and contributions.
Making the case to reinvest in the public good will require a long, hard slog. It will be much harder than the campaign for Open Access and Open Data because it will mean contesting Neoliberal ideologies and constituencies that are deeply entrenched in our institutions. However, the constituencies harmed by Neoliberalism, particularly the student community now burdened by over $1 trillion in debt and the middle class more generally, are much larger and very much aware that something is badly amiss. As we celebrate the impressive strides made by the Open Movement in the past year, it’s time we broaden our goals to tackle the needs for wider reform in the financing and organization of research and education.
This post originally appeared on Digging Digitally and is reposted under a CC-BY license.”

Online Video Game Plugs Players Into Real Biochemistry Lab


Science Now: “Crowdsourcing is the latest research rage—Kickstarter to raise funding, screen savers that number-crunch, and games to find patterns in data—but most efforts have been confined to the virtual lab of the Internet. In a new twist, researchers have now crowdsourced their experiments by connecting players of a video game to an actual biochemistry lab. The game, called EteRNA, allows players to remotely carry out real experiments to verify their predictions of how RNA molecules fold. The first big result: a study published this week in the Proceedings of the National Academy of Sciences, bearing the names of more than 37,000 authors—only 10 of them professional scientists. “It’s pretty amazing stuff,” says Erik Winfree, a biophysicist at the California Institute of Technology in Pasadena.
Some see EteRNA as a sign of the future for science, not only for crowdsourcing citizen scientists but also for giving them remote access to a real lab. “Cloud biochemistry,” as some call it, isn’t just inevitable, Winfree says: It’s already here. DNA sequencing, gene expression testing, and many biochemical assays are already outsourced to remote companies, and any “wet lab” experiment that can be automated will be automated, he says. “Then the scientists can focus on the non-boring part of their work.”
EteRNA grew out of an online video game called Foldit. Created in 2008 by a team led by David Baker and Zoran Popović, a molecular biologist and computer scientist, respectively, at the University of Washington, Seattle, Foldit focuses on predicting the shape into which a string of amino acids will fold. By tweaking virtual strings, Foldit players can surpass the accuracy of the fastest computers in the world at predicting the structure of certain proteins. Two members of the Foldit team, Adrien Treuille and Rhiju Das, conceived of EteRNA back in 2009. “The idea was to make a version of Foldit for RNA,” says Treuille, who is now based at Carnegie Mellon University in Pittsburgh, Pennsylvania. Treuille’s doctoral student Jeehyung Lee developed the needed software, but then Das persuaded them to take it a giant step further: hooking players up directly to a real-world, robot-controlled biochemistry lab. After all, RNA can be synthesized and its folded-up structure determined far more cheaply and rapidly than protein can.
Lee went back to the drawing board, redesigning the game so that it had not only a molecular design interface like Foldit, but also a laboratory interface for designing RNA sequences for synthesis, keeping track of hypotheses for RNA folding rules, and analyzing data to revise those hypotheses. By 2010, Lee had a prototype game ready for testing. Das had the RNA wet lab ready to go at Stanford University in Palo Alto, California, where he is now a professor. All they lacked were players.
A message to the Foldit community attracted a few hundred players. Then in early 2011, The New York Times wrote about EteRNA and tens of thousands of players flooded in.
The game comes with a detailed tutorial and a series of puzzles involving known RNA structures. Only after winning 10,000 points do you unlock the ability to join EteRNA’s research team. There the goal is to design RNA sequences that will fold into a target structure. Each week, eight sequences are chosen by vote and sent to Stanford for synthesis and structure determination. The data that come back reveal how well the sequences’ true structures matched their targets. That way, Treuille says, “reality keeps score.” The players use that feedback to tweak a set of hypotheses: design rules for determining how an RNA sequence will fold.
Two years and hundreds of RNA structures later, the players of EteRNA have proven themselves to be a potent research team. Of the 37,000 who played, about 1000 graduated to participating in the lab for the study published today. (EteRNA now has 133,000 players, 4000 of them doing research.) They generated 40 new rules for RNA folding. For example, at the junctions between different parts of the RNA structure—such as between a loop and an arm—the players discovered that it is far more stable if enriched with guanines and cytosines, the strongest bonding of the RNA base pairs. To see how well those rules describe reality, the humans then competed toe to toe against computers in a new series of RNA structure challenges. The researchers distilled the humans’ 40 rules into an algorithm called EteRNA Bot.”

Belonging: Solidarity and Division in Modern Societies


New book by Montserrat Guibernau: “It is commonly assumed that we live in an age of unbridled individualism, but in this important new book Montserrat Guibernau argues that the need to belong to a group or community – from peer groups and local communities to ethnic groups and nations – is a pervasive and enduring feature of modern social life.
The power of belonging stems from the potential to generate an emotional attachment capable of fostering a shared identity, loyalty and solidarity among members of a given community. It is this strong emotional dimension that enables belonging to act as a trigger for political mobilization and, in extreme cases, to underpin collective violence.
Among the topics examined in this book are identity as a political instrument; emotions and political mobilization; the return of authoritarianism and the rise of the new radical right; symbols and the rituals of belonging; loyalty, the nation and nationalism. It includes case studies from Britain, Spain, Catalonia, Germany, the Middle East and the United States.”

How a New Science of Cities Is Emerging from Mobile Phone Data Analysis


MIT Technology Review: “Mobile phones have generated enormous insight into the human condition thanks largely to the study of the data they produce. Mobile phone companies record the time of each call, the caller and receiver ids, as well as the locations of the cell towers involved, among other things.
The combined data from millions of people produces some fascinating new insights in the nature of our society. Anthropologists have crunched it to reveal human reproductive strategiesa universal law of commuting and even the distribution of wealth in Africa.
Today, computer scientists have gone one step further by using mobile phone data to map the structure of cities and how people use them throughout the day. “These results point towards the possibility of a new, quantitative classification of cities using high resolution spatio-temporal data,” say Thomas Louail at the Institut de Physique Théorique in Paris and a few pals.
They say their work is part of a new science of cities that aims to objectively measure and understand the nature of large population centers.
These guys begin with a database of mobile phone calls made by people in the 31 Spanish cities that have populations larger than 200,000. The data consists of the number of unique individuals using a given cell tower (whether making a call or not) for each hour of the day over almost two months….The results reveal some fascinating patterns in city structure. For a start, every city undergoes a kind of respiration in which people converge into the center and then withdraw on a daily basis, almost like breathing. And this happens in all cities. This “suggests the existence of a single ‘urban rhythm’ common to all cities,” say Louail and co.
During the week, the number of phone users peaks at about midday and then again at about 6 p.m. During the weekend the numbers peak a little later: at 1 p.m. and 8 p.m. Interestingly, the second peak starts about an hour later in western cities, such as Sevilla and Cordoba.
The data also reveals that small cities tend to have a single center that becomes busy during the day, such as the cities of Salamanca and Vitoria.
But it also shows that the number of hotspots increases with city size; so-called polycentric cities include Spain’s largest, such as Madrid, Barcelona, and Bilboa.
That could turn out to be useful for automatically classifying cities.
There is a growing interest in the nature of cities, the way they evolve and how their residents use them. The goal of this new science is to make better use of these spaces that more than 50 percent of the planet inhabit. Louail and co show that mobile phone data clearly has an important role to play in this endeavor to better understanding these complex giants.
Ref: arxiv.org/abs/1401.4540 : From Mobile Phone Data To The Spatial Structure Of Cities”