The Promise of Data-Driven Drug Development


Report by the Center for Data Innovation: “From screening chemical compounds to optimizing clinical trials to improving post-market surveillance of drugs, the increased use of data and better analytical tools such as artificial intelligence (AI) hold the potential to transform drug development, leading to new treatments, improved patient outcomes, and lower costs. However, achieving the full promise of data-driven drug development will require the U.S. federal government to address a number of obstacles. This should be a priority for policymakers for two main reasons. First, enabling data-driven drug development will accelerate access to more effective and affordable treatments. Second, the competitiveness of the U.S. biopharmaceutical industry is at risk so long as these obstacles exist. As other nations, particularly China, pursue data-driven innovation, especially greater use of AI, foreign life sciences firms could become more competitive at drug development….(More)”.

‘Digital colonialism’: why some countries want to take control of their people’s data from Big Tech


Jacqueline Hicks at the Conversation: “There is a global standoff going on about who stores your data. At the close of June’s G20 summit in Japan, a number of developing countries refused to sign an international declaration on data flows – the so-called Osaka Track. Part of the reason why countries such as India, Indonesia and South Africa boycotted the declaration was because they had no opportunity to put their own interests about data into the document.

With 50 other signatories, the declaration still stands as a statement of future intent to negotiate further, but the boycott represents an ongoing struggle by some countries to assert their claim over the data generated by their own citizens.

Back in the dark ages of 2016, data was touted as the new oil. Although the metaphor was quickly debunked it’s still a helpful way to understand the global digital economy. Now, as international negotiations over data flows intensify, the oil comparison helps explain the economics of what’s called “data localisation” – the bid to keep citizens’ data within their own country.

Just as oil-producing nations pushed for oil refineries to add value to crude oil, so governments today want the world’s Big Tech companies to build data centres on their own soil. The cloud that powers much of the world’s tech industry is grounded in vast data centres located mainly around northern Europe and the US coasts. Yet, at the same time, US Big Tech companies are increasingly turning to markets in the global south for expansion as enormous numbers of young tech savvy populations come online….(More)”.

Digital Media and Wireless Communication in Developing Nations: Agriculture, Education, and the Economic Sector


Book by Megh R. Goyal and Emmanuel Eilu: “… explores how digital media and wireless communication, especially mobile phones and social media platforms, offer concrete opportunities for developing countries to transform different sectors of their economies. The volume focuses on the agricultural, economic, and education sectors. The chapter authors, mostly from Africa and India, provide a wealth of information on recent innovations, the opportunities they provide, challenges faced, and the direction of future research in digital media and wireless communication to leverage transformation in developing countries….(More)”.

A fairer way forward for AI in health care


Linda Nordling at Nature: “When data scientists in Chicago, Illinois, set out to test whether a machine-learning algorithm could predict how long people would stay in hospital, they thought that they were doing everyone a favour. Keeping people in hospital is expensive, and if managers knew which patients were most likely to be eligible for discharge, they could move them to the top of doctors’ priority lists to avoid unnecessary delays. It would be a win–win situation: the hospital would save money and people could leave as soon as possible.

Starting their work at the end of 2017, the scientists trained their algorithm on patient data from the University of Chicago academic hospital system. Taking data from the previous three years, they crunched the numbers to see what combination of factors best predicted length of stay. At first they only looked at clinical data. But when they expanded their analysis to other patient information, they discovered that one of the best predictors for length of stay was the person’s postal code. This was puzzling. What did the duration of a person’s stay in hospital have to do with where they lived?

As the researchers dug deeper, they became increasingly concerned. The postal codes that correlated to longer hospital stays were in poor and predominantly African American neighbourhoods. People from these areas stayed in hospitals longer than did those from more affluent, predominantly white areas. The reason for this disparity evaded the team. Perhaps people from the poorer areas were admitted with more severe conditions. Or perhaps they were less likely to be prescribed the drugs they needed.

The finding threw up an ethical conundrum. If optimizing hospital resources was the sole aim of their programme, people’s postal codes would clearly be a powerful predictor for length of hospital stay. But using them would, in practice, divert hospital resources away from poor, black people towards wealthy white people, exacerbating existing biases in the system.

“The initial goal was efficiency, which in isolation is a worthy goal,” says Marshall Chin, who studies health-care ethics at University of Chicago Medicine and was one of the scientists who worked on the project. But fairness is also important, he says, and this was not explicitly considered in the algorithm’s design….(More)”.

Social Systems Evidence


Social Systems Evidence is the world’s most comprehensive, continuously updated repository of syntheses of research evidence about the programs, services and products available in a broad range of government sectors and program areas (e.g., climate action, community and social services, economic development and growth, education, environmental conservation, education, housing and transportation) as well as the governance, financial and delivery arrangements within which these programs, services and products are provided, and the implementation strategies that can help to ensure that these programs, services and products get to those who need them. The content contained in Social Systems Evidence covers the Sustainable Development Goals, with the exceptions of the health part of goal 3 (which is already well covered by databases such as ACCESSSS for clinical evidence, Health Evidence for public health evidence, and Health Systems Evidence for the governance, financial and delivery arrangements, and the implementation strategies that determine whether the right programs, services and products get to those who need them).

The types of syntheses in Social Systems Evidence include evidence briefs for policy, overviews of systematic reviews, systematic reviews, systematic reviews in progress (i.e. protocols for systematic reviews), and systematic reviews being planned (i.e. registered titles for systematic reviews). Social Systems Evidence also contains a continuously updated repository of economic evaluations in these same domains.

Documents included in Social Systems Evidence are identified through weekly electronic searches of online bibliographic databases (EBSCOhost, ProQuest and Web of Science) and through manual searches of the websites of high-volume producers of research syntheses relevant to social-system program and service areas (see acknowledgements below).

For all types of documents, Social Systems Evidence provides links to user-friendly summaries, scientific abstracts, and full-text reports (if applicable and when freely available). For each systematic review, Social Systems Evidence also provides an assessment of its methodological quality, and links to the studies contained in the review.

While SSE is free to use and does not require that users have an account, creating an account will allow you to view more than 20 search results, to save documents and searches, and to subscribe to email alerts, among other advanced features. You can create an account by clicking ‘Create account’ on the top banner (for desktop and laptop computers) or in the menu on far right of the banner (for mobile devices).

Social Systems Evidence can save social-system policymakers and stakeholders a great deal of time by helping them to rapidly identify: a synthesis of the best available research evidence on a given topic that has been prepared in a systematic and transparent way, how recently the search for studies was conducted, the quality of the synthesis, the countries in which the studies included in the synthesis were conducted, and the key findings from the synthesis. Social Systems Evidence can also help them to rapidly identify economic evaluations in these same domains…(More)”.

The Global Disinformation Order: 2019 Global Inventory of Organised Social Media Manipulation


Report by Philip Howard and Samantha Bradshaw: “…The report explores the tools, capacities, strategies and resources employed by global ‘cyber troops’, typically government agencies and political parties, to influence public opinion in 70 countries.

Key findings include:

  • Organized social media manipulation has more than doubled since 2017, with 70 countries using computational propaganda to manipulate public opinion.
  • In 45 democracies, politicians and political parties have used computational propaganda tools by amassing fake followers or spreading manipulated media to garner voter support.
  • In 26 authoritarian states, government entities have used computational propaganda as a tool of information control to suppress public opinion and press freedom, discredit criticism and oppositional voices, and drown out political dissent.
  • Foreign influence operations, primarily over Facebook and Twitter, have been attributed to cyber troop activities in seven countries: China, India, Iran, Pakistan, Russia, Saudi Arabia and Venezuela.
  • China has now emerged as a major player in the global disinformation order, using social media platforms to target international audiences with disinformation.
  • 25 countries are working with private companies or strategic communications firms offering a computational propaganda as a service.
  • Facebook remains the platform of choice for social media manipulation, with evidence of formally organised campaigns taking place in 56 countries….

The report explores the tools and techniques of computational propaganda, including the use of fake accounts – bots, humans, cyborgs and hacked accounts – to spread disinformation. The report finds:

  • 87% of countries used human accounts
  • 80% of countries used bot accounts
  • 11% of countries used cyborg accounts
  • 7% of countries used hacked or stolen accounts…(More)”.

Growth: From Microorganisms to Megacities


Book by Vaclav Smil: “Growth has been both an unspoken and an explicit aim of our individual and collective striving. It governs the lives of microorganisms and galaxies; it shapes the capabilities of our extraordinarily large brains and the fortunes of our economies. Growth is manifested in annual increments of continental crust, a rising gross domestic product, a child’s growth chart, the spread of cancerous cells. In this magisterial book, Vaclav Smil offers systematic investigation of growth in nature and society, from tiny organisms to the trajectories of empires and civilizations.

Smil takes readers from bacterial invasions through animal metabolisms to megacities and the global economy. He begins with organisms whose mature sizes range from microscopic to enormous, looking at disease-causing microbes, the cultivation of staple crops, and human growth from infancy to adulthood. He examines the growth of energy conversions and man-made objects that enable economic activities—developments that have been essential to civilization. Finally, he looks at growth in complex systems, beginning with the growth of human populations and proceeding to the growth of cities. He considers the challenges of tracing the growth of empires and civilizations, explaining that we can chart the growth of organisms across individual and evolutionary time, but that the progress of societies and economies, not so linear, encompasses both decline and renewal. The trajectory of modern civilization, driven by competing imperatives of material growth and biospheric limits, Smil tells us, remains uncertain….(More)”.

Great Policy Successes


Book by Mallory Compton and Edited by Paul ‘t Hart: “With so much media and political criticism of their shortcomings and failures, it is easy to overlook the fact that many governments work pretty well much of the time. Great Policy Successes turns the spotlight on instances of public policy that are remarkably successful. It develops a framework for identifying and assessing policy successes, paying attention not just to their programmatic outcomes but also to the quality of the processes by which policies are designed and delivered, the level of support and legitimacy they attain, and the extent to which successful performance endures over time. The bulk of the book is then devoted to 15 detailed case studies of striking policy successes from around the world, including Singapore’s public health system, Copenhagen and Melbourne’s rise from stilted backwaters to the highly liveable and dynamic urban centres they are today, Brazil’s Bolsa Familia poverty relief scheme, the US’s GI Bill, and Germany’s breakthrough labour market reforms of the 2000s. Each case is set in context, its main actors are introduced, key events and decisions are described, the assessment framework is applied to gauge the nature and level of its success, key contributing factors to success are identified, and potential lessons and future challenges are identified. Purposefully avoiding the kind of heavy theorizing that characterizes many accounts of public policy processes, each case is written in an accessible and narrative style ideally suited for classroom use in conjunction with mainstream textbooks on public policy design, implementation, and evaluation….(More)”.

GovChain


Introduction to Report by Tom Rodden: “This report addresses the most discussed digital technologies of the last few years. There has been considerable debate about the potential benefits and threats that arise from the use of Distributed Ledger Technologies. What is clear from these debates is that blockchain is an important technology that has the potential to transform a range of sectors. The importance of Distributed Ledger Technology was identified and discussed in a 2016 report produced by Sir Mark Walport, the UK Government’s Chief Scientific Adviser at the time.

The report provided recommendations for the use of blockchain to meet national needs, and to ensure the UK’s competitiveness in the global arena. The report outlined the need for a broad response that spanned the public and private sector, whilst also recognising the need for leadership in the development and deployment of blockchain technologies.

This report provides an update and reflection on the use of blockchain technologies by Governments and Public Sector bodies around the world. Much has happened since 2016 and this report provides a reminder of the importance of Distributed Ledger Technologies for the public sector, and the various orientations of blockchains adopted across the globe. The team have mapped the various regulatory and policy responses to blockchain, and cryptocurrencies more broadly. This mapping not only reveals a varying degree of friendliness towards blockchain, it also highlights the challenges involved in implementing Distributed Ledger Technology systems in the public sector.

Distributed Ledger Technologies are an important technology for the public sector, albeit there exists a number of policy implications. If we are to show leadership in the use of blockchain and its application it is imperative that we are aware of both its benefits and limitations; and the issues that need to be addressed to ensure we gain value from the use of Distributed Ledger Technologies. This report captures the public sector experiences of blockchain technologies across the globe, and also documents the issues raised and the various responses. This is a hugely informative and useful document for those who seek to make use of blockchains in the public sector….(More)”.

Counting on the World to Act


Home report cover

Report by Trends: “Eradicating poverty and hunger, ensuring quality education, instituting affordable and clean energy, and more – the Sustainable Development Goals (SDGs) lay out a broad, ambitious vision for our world. But there is one common denominator that cuts across this agenda: data. Without timely, relevant, and disaggregated data, policymakers and their development partners will be unprepared to turn their promises into reality for communities worldwide. With only eleven years left to meet the goals, it is imperative that we focus on building robust, inclusive, and relevant national data systems to support the curation and promotion of better data for sustainable development. In Counting on the World to Act, TReNDS details an action plan for governments and their development partners that will enable them to help deliver the SDGs globally by 2030. Our recommendations specifically aim to empower government actors – whether they be national statisticians, chief data scientists, chief data officers, ministers of planning, or others concerned with evidence in support of sustainable development – to advocate for, build, and lead a new data ecosystem….(More)”.